NAD+ IV Drip vs
Myers Cocktail

An NAD+ IV drip gives a single ingredient, the coenzyme NAD+, slowly over 90 to 120 minutes, while a Myers cocktail is a quicker vitamin and mineral drip of B vitamins, vitamin C, magnesium and calcium that takes about 45 minutes. They are different products, not stronger or weaker versions of the same thing. At mobivIVe, MobiNAD+ 250mg costs R1,300 (about 90 minutes) and MobiNAD+ 500mg costs R1,950 (about 120 minutes), both given slowly in a small 200ml saline bag. Our Myers cocktail, the Dr John Myers drip, costs R1,050 and takes about 45 minutes. Every drip is given by a registered nurse after a medical screening questionnaire, under the protocols of our medical director, Dr Chris van Zyl. This guide compares what is in each drip, how each feels during the infusion, what the evidence honestly says, who tends to choose which, and how the two can be combined.

This guide was written under the medical direction of Dr Chris van Zyl (registered as M.C. van Zyl, HPCSA MP0287067), mobivIVe’s medical director. Our IV drips are given by registered nurses after a medical screening questionnaire.

What is the difference between an NAD+ drip and a Myers cocktail?

An NAD+ drip contains one coenzyme given slowly, while a Myers cocktail is a blend of vitamins and minerals given at a normal drip pace. Here is how our two drips compare:

Injectable vitamins and NAD+ are Schedule 3 medicines in South Africa, so a registered nurse gives both drips after a medical screening questionnaire, under the protocols of our medical director, Dr Chris van Zyl. Neither drip is a substitute for seeing your own doctor about a health concern.

What is an NAD+ IV drip?

An NAD+ IV drip delivers NAD+ (nicotinamide adenine dinucleotide), a coenzyme found in every cell, straight into a vein. In the body, NAD+ helps the enzymes that turn food into usable energy, and it is also used by enzymes involved in DNA repair and cell signalling. The body builds its own NAD+ from niacin (vitamin B3) and other building blocks in food. MobiNAD+ contains NAD+ only, with no added vitamins, and runs slowly in a 200ml saline bag: about 90 minutes for 250mg (R1,300) and about 120 minutes for 500mg (R1,950). For the background, read What is NAD+? and see prices and times on our NAD+ IV drip page.

What is a Myers cocktail?

A Myers cocktail is an IV drip of B vitamins, vitamin C, magnesium and calcium, named after the late Dr John Myers, the doctor whose formula it builds on. In general terms, B vitamins help the body release energy from food, vitamin C is an antioxidant the body needs to make collagen, and magnesium and calcium are minerals involved in muscle and nerve function. Our version, the Dr John Myers drip, costs R1,050 and takes about 45 minutes, with a choice of a 200ml or 1000ml saline bag at no extra cost. The Myers cocktail is also the base of several of our other drips. Read more in our guide What is a Myers cocktail?

How does each drip feel during the infusion?

A Myers cocktail usually feels like an ordinary drip, while NAD+ can cause uncomfortable sensations if it runs too fast, which is why we always give it slowly. In a 2026 retrospective study in Frontiers in Aging, all six people who received 500mg NAD+ by drip reported sensations during the infusion, including stomach cramping, nausea, a faster heart rate and chest pressure. These stopped when each infusion ended, and participants slowed their drips, which then averaged about 97 minutes. The study was very small and run by a commercial IV clinic. With a Myers cocktail, some people notice a passing warm feeling. With either drip, tell the nurse straight away if you feel discomfort so the rate can be adjusted.

What does the evidence say about NAD+ drips?

NAD+ clearly matters to the body, but human evidence for NAD+ drips as a wellness routine is still limited. A 2026 systematic review in Ageing Research Reviews looked at 33 human intervention studies and found that oral NAD+ precursors, such as nicotinamide riboside, raised NAD-related markers in the blood, but effects on health outcomes were mixed and often showed no difference. The reviewers found no eligible outcome trials of intravenous or intramuscular NAD+ itself, and called for larger, well-designed trials, particularly for injected routes. We therefore make no promises about results, and we do not claim that an NAD+ drip treats, cures or prevents any condition.

What does the evidence say about the Myers cocktail?

Evidence for the Myers cocktail is limited and mostly comes from small studies. The main placebo-controlled study, a 2009 pilot trial from Yale, gave 34 adults with fibromyalgia weekly Myers drips or a placebo drip for eight weeks. Both groups reported improvements, but there was no statistically significant difference between them, and the authors described the benefit as uncertain. A 2023 article in the Drug and Therapeutics Bulletin concluded there is a lack of high-quality evidence that high-dose vitamin infusions offer a health benefit without a specific deficiency or medical condition. We describe the Dr John Myers drip as a hydration and vitamin top-up, nothing more.

Who usually chooses NAD+, and who chooses a Myers cocktail?

People who want a slow, unhurried session built around NAD+ tend to choose MobiNAD+, while people who want a quicker hydration and vitamin top-up tend to choose the Myers cocktail. MobiNAD+ is popular with busy professionals who block out 90 to 120 minutes as a wellness ritual, and with people following one of our NAD+ programmes. The Dr John Myers drip suits people who want something shorter and lower in price: before a big event, after a long-haul flight or during a demanding week. It also fits more easily into a busy day. If you would like more fluid, the Myers drip can run in a 1000ml bag, while NAD+ always runs in a 200ml bag.

Can I combine NAD+ with a Myers cocktail?

Yes, and our Elite NAD+ Programme (R10,600) pairs MobiNAD+ 250mg with The Royal IV, which contains the Myers cocktail. The Royal IV (R2,650, about 45 minutes) is our all-in-one drip: alongside the Myers cocktail of B vitamins, magnesium and calcium, it includes vitamin C, glutathione, alpha lipoic acid, selenium and zinc, L-carnitine, glutamine and more. Because NAD+ is always run slowly, the nurse plans the timing of each drip with you. Other NAD+ programmes include the Reverse Aging Programme (R9,320) and the Athletic Endurance and Performance Programme (R9,100). Tell the nurse about every medicine and supplement you take before combining drips.

How much does each drip cost?

The Dr John Myers drip costs R1,050, MobiNAD+ 250mg costs R1,300 and MobiNAD+ 500mg costs R1,950 per drip. Time is the other big difference: about 45 minutes for the Myers drip, about 90 minutes for NAD+ 250mg and about 120 minutes for NAD+ 500mg. The Myers drip comes with a choice of a 200ml or 1000ml saline bag at no extra cost (1000ml with dextrose is R200 extra), and extra vitamins can be added. Mobile visits carry a call-out fee of R400 minimum, or R150 per person for groups (first 15km). Programmes, such as the Elite NAD+ Programme at R10,600, are priced as a package.

Who should check with us first, and how do I book?

Anyone with a heart, kidney or liver condition, anyone who is pregnant, and anyone on chronic medication must tell us before booking either drip. Every drip is given by a registered nurse after a medical screening questionnaire, under the protocols of our medical director, Dr Chris van Zyl. You can walk into our lounges in Sunninghill (Johannesburg), Stellenbosch or Queenstown (Komani), or a nurse can come to your home, office, hotel or event in Johannesburg, the Winelands or Cape Town. Book online at book.mobivive.co.za and choose a lounge, or “Your Home, Office, etc.” for a mobile visit. If you are unsure which drip suits you, WhatsApp or call us on 061 509 6038.