5-Amino-1-MQ is a metabolic peptide used to support fat metabolism, healthy cholesterol and cellular energy. It is popular as an add-on for people who have hit a plateau on a weight-loss programme. At mobivIVe, doctor-reviewed 5-Amino-1-MQ is supplied as a prefilled pen from R1,650, delivered nationwide across South Africa. Below is what it does, who it suits, what it costs, and how to get started with our doctor-led team. New to 5-Amino-1-MQ? Read our full guide on what 5-Amino-1-MQ is and how it works.
What it does. 5-Amino-1-MQ blocks an enzyme called NNMT (nicotinamide N-methyltransferase) that is overactive in fat tissue. By inhibiting NNMT, emerging research suggests it can raise cellular NAD+ levels and switch fat cells toward burning rather than storing energy, which is why it is studied for fat loss and metabolic health. It is often used to complement a GLP-1 weight-loss programme.
Who it suits. 5-Amino-1-MQ appeals to people focused on fat loss and metabolic health, particularly those who have stalled on diet, training or a GLP-1 programme and want an additional, doctor-guided metabolic lever. It pairs naturally with our medical weight-loss options.
How to start, in 3 simple steps
Message us on WhatsApp. Tell our doctor-led team your goal.
Medical questionnaire. Complete a short questionnaire, reviewed by our registered doctor. A consultation is arranged when your screening calls for one. If it is safe and suitable, a script is issued.
Delivered to your door. Your prefilled pen is couriered anywhere in South Africa, with clear dosing instructions.
Is it right for me? 5-Amino-1-MQ suits people wanting extra support with fat metabolism as part of a medically-guided routine, especially alongside diet, training or a GLP-1 programme. Our doctor screens for anything that needs extra care and asks about your history and current medicines, so it can be checked before anything is dispensed. Tell us if you are pregnant, breastfeeding, or have an active cancer.
Price: R1,650 (incl. VAT) Strength: 0.9mg/0.6ml (3ml pen) – 4.5mg total Approx. doses: 30 doses at 150mcg
What it is
5-Amino-1-MQ is a small-molecule peptide that inhibits the NNMT enzyme, shifting metabolism towards greater fat burning, better cholesterol handling and improved NAD+ availability. It supports clients who want to improve body composition and metabolic health without stimulants, and works particularly well alongside diet, exercise and, where appropriate, GLP1 or NAD+ programmes.
Used for
Stubborn fat loss (especially mid-section) in combination with lifestyle changes
Supporting healthier cholesterol and triglyceride profiles
Enhancing NAD+-related energy and longevity protocols
Weight-loss plateaus where calories and training are already dialled in
Clients who want metabolic help without jittery stimulant products
5-Amino-1-MQ is a small molecule that inhibits NNMT, an enzyme overactive in fat tissue. By blocking NNMT, emerging research suggests it raises cellular NAD+ and shifts fat cells toward burning energy. It is used as a metabolic support, and its evidence so far is largely preclinical.
By inhibiting NNMT it is thought to improve how fat cells handle energy and to support NAD+ levels, which are involved in metabolism. In practice it is used as a complementary lever for people who have plateaued, alongside diet, training or a GLP-1 programme, rather than as a standalone weight-loss cure.
It is often used to complement a GLP-1 weight-loss programme, and your doctor decides whether combining them suits your situation. See our medical weight-loss options for the GLP-1 side.
It is generally well tolerated in the available research, with side effects usually limited to mild injection-site reactions. Honestly, the evidence is still largely preclinical, so it is best understood as doctor-supervised metabolic support rather than an established treatment, with realistic expectations.
At mobivIVe, doctor-reviewed 5-Amino-1-MQ starts from R1,650 per prefilled pen. Yes, it is dispensed on a valid medical script after a questionnaire reviewed by our registered doctor, with a consultation arranged when your screening calls for one.
Medically reviewed by Dr Chris van Zyl This page was written and reviewed by mobivIVe’s medical team, led by Dr Chris van Zyl, an HPCSA-registered medical doctor (registered as M.C. van Zyl, HPCSA reg. no. MP0287067) who is licensed to both prescribe and dispense medicines under a Section 22C dispensing licence. Last reviewed August 2026. Not intended to diagnose, treat, cure or prevent any disease; individual results vary. Consult your healthcare provider.
