Doctor-Led Weight Management

Tirzepatide & Mounjaro
in South Africa

Tirzepatide, the active ingredient in Mounjaro, is a doctor-prescribed weekly injection for weight management. At mobivIVe, we offer doctor-reviewed compounded tirzepatide, delivered nationwide across South Africa from R3,199. Below is what it costs, who qualifies, and how to get started. Every order is guided by a registered doctor over WhatsApp and includes a required telephone or virtual consultation before any GLP-1 is dispensed. New to GLP-1 weight loss? Read our doctor-led guide to medical weight loss in South Africa.

How tirzepatide works. Tirzepatide is a dual-action medicine that targets two gut hormones at once, GLP-1 and GIP. This dual mechanism reduces appetite, slows stomach emptying and steadies blood sugar, and in clinical use tends to deliver stronger weight-loss results than single-hormone GLP-1s such as semaglutide, making it a powerful option for clients who need more metabolic support.

Tirzepatide vs Mounjaro. Mounjaro is the original branded tirzepatide; the compounded tirzepatide we dispense delivers the same active molecule at a more affordable price. It is supplied as an easy-to-use prefilled cartridge pen, no vials, no mixing, with your dose titrated slowly by our doctor to keep side-effects low.

How to start, in 3 simple steps

  1. Message us on WhatsApp. Tell our doctor-led team your goal.
  2. Medical questionnaire & doctor consultation. Complete a short questionnaire, then a telephone or virtual consultation with our registered doctor, which is required for all GLP-1 medicines (tirzepatide, Mounjaro, semaglutide and Ozempic). If it is safe and suitable, a script is issued.
  3. Delivered to your door. Your prefilled pen is couriered anywhere in South Africa, and you begin your weekly routine.

Am I eligible? You may be a good candidate if you want structured, medically-supervised weight loss and can self-inject a weekly pen. Because tirzepatide (Mounjaro) is a prescription GLP-1/GIP medicine, a telephone or virtual doctor consultation is required for every order, because it cannot be dispensed without one. During screening we also check for conditions that need extra care, such as a history of certain thyroid or pancreatic conditions, pregnancy, breastfeeding or planning pregnancy, significant heart, kidney or liver disease, or medicines that may interact.

Tirzepatide & Mounjaro, options & prices

Price: R3,199 (incl. VAT)
Strength: 5mg/0.6ml (2.4ml pen) – 20mg total
Approx. duration: 4 doses (4 weeks at 5mg/week)

What it is
Tirzepatide is a dual-action peptide that activates both GLP-1 and GIP receptors, giving it powerful effects on appetite, insulin sensitivity and weight loss. The 5mg strength is typically used as an initial or moderate dose, delivering strong appetite control and improved post-meal glucose handling with once-weekly injections. It’s an excellent choice for clients who need more metabolic support than semaglutide alone, or who want the latest dual-agonist technology for weight management.

Used for

  • Weightloss clients needing more robust effects than standard GLP-1
  • Insulin resistance and metabolic syndrome under medical supervision
  • Reducing visceral/central fat and waist circumference
  • Breaking plateaus after previous weight-loss attempts
  • Early to midrange tirzepatide protocols (starter/stepup dose)

Price: R4,999 (incl. VAT)
Strength: 10mg/0.6ml (2.4ml pen) – 40mg total
Approx. duration: 8 weeks at 5mg or 4 weeks at 10mg

What it is
The 10mg tirzepatide pen is designed for higher-dose, advanced dual-agonist protocols after a client has already titrated and tolerated lower doses. By strongly activating both GLP-1 and GIP pathways, it provides intense appetite suppression, improved insulin sensitivity and powerful fat-loss support in appropriate candidates. This option is best suited to high-risk or severely overweight clients in structured medical weight-management programmes.

Used for

  • Advanced tirzepatide protocols at higher maintenance doses
  • Severe obesity and high cardiometabolic risk profiles
  • Clients needing stronger appetite and glucose control after GLP-1s
  • Long-term bodyweight and metabolic transformation plans
  • Consolidating and maintaining large weight-loss achievements

Frequently asked questions

At mobivIVe, doctor-reviewed compounded tirzepatide starts from R3,199 per prefilled pen, with a higher-strength 10mg pen also available. A telephone or virtual doctor consultation is required for all GLP-1 medicines before a script can be issued.

Yes. Tirzepatide is a prescription medicine and cannot be sold without a consultation. You complete a short medical questionnaire and then have a telephone or virtual consultation with our registered doctor, who issues a script if it is safe and suitable for you.

Tirzepatide works on two hormones (GLP-1 and GIP) rather than one, and in clinical use it tends to produce greater weight loss than semaglutide for many people. Which is right for you depends on your health, goals and tolerance, which is exactly what your doctor consultation determines.

Yes. Once your script is approved, your prefilled tirzepatide pen is couriered discreetly anywhere in South Africa.

Both contain the same active molecule (tirzepatide). Mounjaro is the branded, imported product; compounded tirzepatide is produced locally as a more cost-effective option, dosed to the same clinical effect on your script.

Medically reviewed by Dr Chris van Zyl This page was written and reviewed by mobivIVe’s medical team, led by Dr Chris van Zyl, an HPCSA-registered medical doctor (registered as M.C. van Zyl, HPCSA reg. no. MP0287067) who is licensed to both prescribe and dispense medicines under a Section 22C dispensing licence. Last reviewed July 2026. Not intended to diagnose, treat, cure or prevent any disease; individual results vary. Consult your healthcare provider.