Semagard is a SAHPRA-registered semaglutide made by Sun Pharma. It contains the same active ingredient as Ozempic and Wegovy, supplied in a dial pen. This page explains what it is, what it costs at mobivIVe, how the dose works, and how to start, reviewed by a registered doctor.
Reviewed by Dr Chris van Zyl (registered as M.C. van Zyl, HPCSA MP0287067), who consults patients himself and dispenses under his own Section 22C dispensing licence.
What is Semagard?
Semagard is semaglutide, a once-weekly GLP-1 receptor agonist that reduces appetite, slows stomach emptying and helps stabilise blood sugar. It is made by Sun Pharma and registered with SAHPRA (registration number 61/21.13/0768) as a Schedule 4 prescription medicine. It is a registered medicine, not a compounded product.
How much does Semagard cost in South Africa?
At mobivIVe the Semagard 1.5ml pen is R1,999 and the 3ml pen is R3,299, including VAT. For a new patient the 1.5ml pen lasts about six weeks and the 3ml pen about eight weeks while the dose is stepped up. A R500 doctor consultation is added to your first order. See how this compares on our weight loss injection price comparison.
How does the Semagard pen work?
Semagard is a dial pen containing 1.34mg of semaglutide per ml. The starting doses are marked on the pen, and your doctor tells you exactly which dose to dial. Treatment usually starts at 0.25mg once a week and is stepped up gradually, typically to 0.5mg and then 1mg, depending on how you tolerate it. Both pen sizes can deliver every dose.
Semagard or Ozempic: what is the difference?
Both contain semaglutide. Ozempic is the original brand made by Novo Nordisk, and Semagard is Sun Pharma’s SAHPRA-registered semaglutide. The active molecule is the same; the main differences are the pen and the price. See Ozempic in South Africa, or compare semaglutide and tirzepatide.
Do I need a prescription for Semagard?
Yes. Semagard is a Schedule 4 prescription medicine and cannot legally be supplied without a script. At mobivIVe every GLP-1 order requires a telephone or video consultation with Dr Chris van Zyl before anything is dispensed.
How do I start?
Message our team on WhatsApp. You will have a telephone or video consultation with our registered doctor, who decides what is clinically appropriate for you. If a script is issued, your Semagard pen is couriered discreetly anywhere in South Africa. Read more about semaglutide in South Africa.
How to start, in 3 simple steps
- Message us on WhatsApp. Tell our doctor-led team your goal.
- Doctor consultation. A telephone or video consultation with our registered doctor, who assesses your suitability and issues a script if the treatment is right for you.
- Delivered to your door. Your prefilled pen is couriered anywhere in South Africa, with clear dosing instructions.
More on weight loss injections: Weight loss injections compared · Mounjaro price · Ozempic price · Semaglutide · Wegovy · Semaglutide vs tirzepatide · Pharmacy vs doctor-led prices
Medically reviewed by Dr Chris van Zyl This page was written and reviewed by the mobivIVe medical team, led by Dr Chris van Zyl, an HPCSA-registered medical doctor (registered as M.C. van Zyl, HPCSA reg. no. MP0287067) who is licensed to both prescribe and dispense medicines under a Section 22C dispensing licence. Last reviewed November 2026. Brand names are the property of their respective owners and are used here for identification only. Prices change, so confirm current pricing before ordering. Not intended to diagnose, treat, cure or prevent any disease; individual results vary.