TB-500 is a regenerative peptide used to support whole-body recovery, mobility and tissue repair. It is a synthetic form of Thymosin Beta-4, and in South Africa it is a prescription item. This page explains what it is, what it costs, the honest state of the evidence, and how to get it properly.
Reviewed by Dr Chris van Zyl (registered as M.C. van Zyl, HPCSA MP0287067), who is licensed to both prescribe and dispense under a Section 22C dispensing licence. This is dispensed on a valid script after a medical questionnaire, with a consultation arranged when your screening calls for one.
What is TB-500?
TB-500 is a synthetic version of a fragment of Thymosin Beta-4, a protein found naturally in the body that plays a role in cell migration and tissue repair. On labels and scripts you may see it written as TB-4, which is the same compound; TB-500 is simply the commercial name.
How much does TB-500 cost in South Africa?
At mobivIVe the TB-500 15mg prefilled pen is R2,699 including VAT, giving roughly 10 to 20 doses depending on the protocol your doctor sets. A combined BPC-157 and TB-500 pen is R2,099. See the full recovery peptides range.
What is TB-500 used for?
It is used as doctor-supervised support for general recovery, mobility and repair across the body, rather than at one specific site. People typically use it after heavy training blocks, during rehabilitation, or when recovery has become the limiting factor. As with BPC-157, it supports rehabilitation rather than replacing it.
What is the honest state of the evidence?
Most of the promising work on TB-500 comes from laboratory and animal research, with limited robust human trial data. Treat it as doctor-supervised recovery support with realistic expectations, not as a proven medicine. Anyone promising you guaranteed results is overselling it.
Why does it matter where you buy TB-500?
Much of the TB-500 sold in South Africa is research-grade material from unregulated suppliers, with no verifiable purity and no dosing guidance. SAHPRA has issued public warnings about unregistered products sold through social media, gyms and salons. At mobivIVe it is dispensed on a valid script by a doctor holding his own Section 22C dispensing licence, in a prefilled pen with clear dosing.
Is TB-500 allowed in sport?
No. TB-500 appears on the WADA Prohibited List, so athletes subject to anti-doping testing should not use it. Raise it with your doctor before starting if you compete.
TB-500 or BPC-157?
TB-500 acts more systemically, across the body. BPC-157 tends to act locally at a specific injury site. Many protocols use both together, which is what the combination pen is for. See our full comparison or the BPC-157 page.
How do I get TB-500 in South Africa?
It is a prescription item, so it starts with a short medical questionnaire reviewed by our registered doctor, with a consultation arranged when your screening calls for one. Once a script is issued, your prefilled pen is couriered anywhere in South Africa with clear dosing instructions.
How to start, in 3 simple steps
- Message us on WhatsApp. Tell our doctor-led team your goal.
- Medical questionnaire. Complete a short questionnaire, reviewed by our registered doctor. A consultation is arranged when your screening calls for one. If it is safe and suitable, a script is issued.
- Delivered to your door. Your prefilled pen is couriered anywhere in South Africa, with clear dosing instructions.
Medically reviewed by Dr Chris van Zyl This page was written and reviewed by the mobivIVe medical team, led by Dr Chris van Zyl, an HPCSA-registered medical doctor (registered as M.C. van Zyl, HPCSA reg. no. MP0287067) who is licensed to both prescribe and dispense medicines under a Section 22C dispensing licence. Last reviewed August 2026. Not intended to diagnose, treat, cure or prevent any disease; individual results vary. Consult your healthcare provider.